Description

Betnovate-C CAS NO 53262-70-7 is a topical pharmaceutical preparation combining a potent corticosteroid with an antimicrobial agent. This combination is critical for effectively treating inflammatory skin conditions where secondary bacterial infection is present or likely. It is primarily required by the pharmaceutical and dermatological sectors for the formulation of prescription-strength creams and ointments.

Application

• Topical Anti-inflammatory & Antimicrobial Therapy: Formulated into creams and ointments for the treatment of eczematous dermatoses, such as atopic eczema and contact dermatitis, complicated by bacterial infection.
• Dermatological Product Development: Serves as a key active pharmaceutical ingredient (API) blend for manufacturers developing specialized prescription dermatological products.
• Hospital & Clinical Formulations: Used in hospital pharmacies for compounding specific topical preparations where combined steroid and antimicrobial action is clinically indicated.
• Veterinary Dermatology: Applied in veterinary medicine for treating similar inflammatory skin conditions in animals where bacterial overgrowth is a concern.

Basic Information

Product Name	Betnovate-C
CAS No.	53262-70-7
Molecular Formula	C24H31FO5 (Betamethasone) + C22H30Cl2N10O3S3 (Clioquinol)
Molecular Weight	392.46 g/mol (Betamethasone) + 415.33 g/mol (Clioquinol)
Synonyms	Betamethasone/Clioquinol; Betamethasone Dipropionate and Clioquinol; Betamethasone 17,21-Dipropionate with Iodochlorhydroxyquin; Clioquinol and Betamethasone Dipropionate; Betnovate C Cream; Betnesol-C; IODOCLORHYDROXYQUIN AND BETAMETHASONE; Betamethasone Dipropionate Mixture with Clioquinol (3:1)
EINECS	Contact for details

Quality Control

Our Betnovate-C is manufactured and tested to meet stringent pharmaceutical standards. Every batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC and other pharmacopoeial methods, to ensure the correct ratio and purity of both active components. A Certificate of Analysis (COA) documenting compliance with relevant specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white cream base mixture
Identification (HPLC/IR)	Conforms to reference standards
Assay (Betamethasone Dipropionate)	90.0% - 110.0% of labeled claim
Assay (Clioquinol)	90.0% - 110.0% of labeled claim
Related Substances (HPLC)	Meets pharmacopoeial limits
Microbial Limits	Complies with USP/EP requirements
pH	As per approved range for cream formulation

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.