Description

Cyclopropanecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester, (1R,2S)-Rel- (9Ci) is a high-purity chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, biologically active molecules, offering precise stereochemical control. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of complex fragrance and flavor ingredients that require high stereochemical purity.
• Academic and Industrial Research: A valuable tool for chemists in universities and corporate R&D labs exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester, (1R,2S)-Rel- (9Ci)
CAS No.	53229-56-4
Molecular Formula	C6H7ClO3
Molecular Weight	162.57 g/mol
Synonyms	(1R,2S)-rel-2-(Chlorocarbonyl)cyclopropanecarboxylic acid methyl ester; Methyl (1R,2S)-rel-2-(chloroformyl)cyclopropanecarboxylate; (1R,2S)-rel-Methyl 2-(chlorocarbonyl)cyclopropanecarboxylate; 2-(Chlorocarbonyl)cyclopropanecarboxylic acid methyl ester, (1R,2S)-rel-; Cyclopropanecarbonyl chloride, 2-(methoxycarbonyl)-, (1R,2S)-rel-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(Chlorocarbonyl)-, Methyl Ester, (1R,2S)-Rel- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the exacting standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after opening to maintain purity and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.