Description

2'-Deoxy-N4,N4-Dimethylcytidine is a chemically modified nucleoside derivative of cytidine, featuring dimethylation at the N4 position of the cytosine base. This specific modification is crucial for applications in medicinal chemistry and biochemical research, where it serves as a key building block or a model compound for studying nucleic acid interactions and metabolism. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, oligonucleotide synthesis, and as a reference standard in analytical development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate DNA/RNA metabolism and repair mechanisms.
• Oligonucleotide Synthesis: Employed in the development of modified antisense oligonucleotides or siRNA for therapeutic and research applications.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in HPLC, LC-MS, and NMR.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to optimize the pharmacokinetic properties of nucleoside-based drugs.
• Academic Research: Fundamental studies in chemical biology exploring the impact of nucleoside modifications on nucleic acid structure and function.

Basic Information

Product Name	2'-Deoxy-N4,N4-Dimethylcytidine
CAS No.	53213-03-9
Molecular Formula	C11H17N3O4
Molecular Weight	255.27 g/mol
Synonyms	N4,N4-Dimethyl-2'-deoxycytidine; 1-(2-Deoxy-β-D-ribofuranosyl)-N4,N4-dimethylcytosine; 2'-Deoxy-N4,N4-dimethylcytidine; N4,N4-Dimethyldeoxycytidine; 2'-Deoxy-N(4),N(4)-dimethylcytidine; dC(N4Me2); N4,N4-Dimethyl-2'-deoxycytidine
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-N4,N4-Dimethylcytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.