Description

5α-Cholestane-3β,6α,15α,24-Tetraol is a high-purity, polyhydroxylated sterol derivative of significant interest in advanced chemical synthesis and research. This compound serves as a crucial intermediate and reference standard for the development and analysis of complex steroidal molecules. It is primarily utilized by research institutions and pharmaceutical development teams working on novel therapeutic agents, metabolic studies, and biochemical pathways. The material is characterized by its specific stereochemistry and hydroxyl group placement, making it valuable for targeted synthetic applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of sterol metabolites in drug development and quality control laboratories.
• Biochemical Research: Serves as a key intermediate or substrate in enzymatic studies, metabolic pathway investigations, and receptor binding assays related to cholesterol and its derivatives.
• Organic Synthesis: Acts as a sophisticated building block for the semi-synthesis of novel steroid analogs with potential biological activity, leveraging its multiple hydroxyl groups for selective functionalization.
• Analytical Chemistry: Employed as an internal standard or calibration compound in chromatographic methods (HPLC, GC-MS) for the accurate measurement of sterols in complex matrices.
• Academic Research: Utilized in universities and research institutes for studies in organic chemistry, medicinal chemistry, and natural product synthesis.

Basic Information

Item	Details
Product Name	5α-Cholestane-3β,6α,15α,24-Tetraol
CAS No.	53190-88-8
Molecular Formula	C27H48O4
Molecular Weight	436.67 g/mol
Synonyms	5α-Cholestane-3β,6α,15α,24-tetrol; (3β,5α,6α,15α,24R)-Cholestane-3,6,15,24-tetrol; 24R,25-Dihydroxycholesterol related compound; Cholestanetetrol; 3β,6α,15α,24-Tetrahydroxy-5α-cholestane
EINECS	Contact for details

Quality Control

Our 5α-Cholestane-3β,6α,15α,24-Tetraol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.