Description

1,1-Cyclopentanedicarbonyldichloride(9Ci) is a high-purity, reactive diacid chloride derivative of cyclopentane, serving as a critical building block in advanced organic synthesis. Its value lies in enabling the efficient introduction of the 1,1-cyclopentanedicarboxylic acid moiety under mild conditions, which is essential for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel active ingredients and functional materials. Consistent quality and reliable supply are paramount for ensuring reproducible results in sensitive multi-step syntheses.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of protease inhibitors, kinase inhibitors, and other small molecule therapeutics featuring constrained, spiro-like, or bridged ring systems.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and fungicides, where the cyclopentane scaffold contributes to improved biological activity and environmental profile.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for producing specialty polyamides, polyesters, and polyimides with enhanced thermal and mechanical properties.
• Material Science: Employed in the synthesis of metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and other porous materials for catalysis and gas storage.
• Ligand and Catalyst Development: Fundamental precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptide Mimetics: Facilitates the incorporation of rigid, non-peptide spacers and turn inducers into peptide backbones for drug discovery.

Basic Information

Item	Detail
Product Name	1,1-Cyclopentanedicarbonyldichloride(9Ci)
CAS No.	53179-95-6
Molecular Formula	C7H8Cl2O2
Molecular Weight	195.04 g/mol
Synonyms	1,1-Cyclopentanedicarbonyl Dichloride; Cyclopentane-1,1-dicarbonyl Dichloride; 1,1-Cyclopentanedicarboxylic Acid Dichloride; Cyclopentane-1,1-dicarboxylic Acid Chloride; 1,1-Bis(chlorocarbonyl)cyclopentane; NSC 163063; 1,1-Cyclopentanedicarboxylic Dichloride
EINECS	Contact for details

Quality Control

Every batch of 1,1-Cyclopentanedicarbonyldichloride is manufactured and tested under a strict quality management system. We guarantee high chemical purity and consistency, with specifications tailored to meet the rigorous demands of process chemistry and cGMP starting material applications where applicable. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.