Description

5-Isopropyl-3-Isoxazolecarbonyl Chloride is a highly reactive acid chloride derivative of an isoxazole heterocycle. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the 5-isopropyl-3-isoxazolecarbonyl moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key reagent for the synthesis of potential drug candidates, particularly in creating amide bonds for protease inhibitors or other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the isoxazole ring system.
• Material Science Research: Acts as a monomer or coupling agent in the creation of specialized polymers and functional materials.
• Peptide Mimetics: Employed to incorporate heterocyclic scaffolds into peptide backbones, modifying their stability and biological activity.
• Ligand and Catalyst Development: Useful for synthesizing complex ligands for metal catalysis or organocatalysts.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	5-Isopropyl-3-Isoxazolecarbonyl Chloride
CAS No.	53064-56-5
Molecular Formula	C7H8ClNO2
Molecular Weight	173.60 g/mol
Synonyms	3-Isoxazolecarbonyl chloride, 5-(1-methylethyl)-; 5-Isopropylisoxazole-3-carbonyl chloride; 5-(Propan-2-yl)-1,2-oxazole-3-carbonyl chloride; 5-Isopropyl-3-carboxyisoxazole chloride; Isoxazole-3-carbonyl chloride, 5-isopropyl-; 53064-56-5; 5-Isopropyl-isoxazole-3-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 5-Isopropyl-3-Isoxazolecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at 2-8°C (refrigerated) or as specified on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.