Description

2-Deoxy-2-Iodo-D-Glucose is a halogenated glucose derivative where an iodine atom replaces the hydroxyl group at the C-2 position. This structural modification makes it a valuable biochemical tool and a key intermediate in the synthesis of more complex molecules, particularly in radiopharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and diagnostic imaging sectors for metabolic studies and tracer synthesis.

Application

• Radiopharmaceutical Precursor: A crucial intermediate in the synthesis of radioiodinated glucose analogs, such as 2-Deoxy-2-[¹⁸F]fluoro-D-glucose (FDG) alternatives, for Positron Emission Tomography (PET) imaging.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate glucose metabolism pathways, particularly those involving hexokinase and glucose transporters.
• Glycobiology Studies: Serves as a building block or modified sugar analog for probing glycosylation processes and carbohydrate-protein interactions.
• Antiviral & Anticancer Agent Development: Investigated as a potential lead compound or intermediate for developing novel therapeutic agents that target cellular glucose uptake in diseased cells.
• Diagnostic Probe Synthesis: Employed in the creation of molecular probes designed to study tumor metabolism and other disorders characterized by altered glucose utilization.
• Organic Synthesis Intermediate: Acts as a chiral starting material for the stereoselective synthesis of complex natural products and other iodinated organic compounds.

Basic Information

Product Name	2-Deoxy-2-Iodo-D-Glucose
CAS No.	53008-75-6
Molecular Formula	C₆H₁₁IO₅
Molecular Weight	290.05 g/mol
Synonyms	2-Deoxy-2-iodo-D-glucose; 2-Iodo-2-deoxy-D-glucose; 2-Iodo-2-deoxyglucose; D-2-Deoxy-2-iodoglucose; 2-Deoxy-2-iodoglucose; 2-Iodo-D-glucose; 53008-75-6; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-iodotetrahydro-2H-pyran-3,4-diol
EINECS	Contact for details

Quality Control

Our 2-Deoxy-2-Iodo-D-Glucose is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific research or cGMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.