Description

4-Pyridyl Thioacetyl Chloride is a versatile and highly reactive organosulfur building block used in advanced organic synthesis. This compound is critical for introducing the 4-pyridylthioacetyl moiety into target molecules, enabling the development of novel chemical entities. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand synthesis, and the creation of functional polymers.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its structural motif can contribute to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Peptide Mimetics and Bioconjugation: Employed to modify peptides or proteins, facilitating the study of biological pathways or the creation of antibody-drug conjugates (ADCs).
• Material Science Research: Utilized in the synthesis of functionalized polymers and advanced materials with specific electronic or surface properties.
• Chemical Biology Probes: Acts as a building block for creating molecular probes that can label or inhibit specific enzymes or cellular processes.

Basic Information

Item	Detail
Product Name	4-Pyridyl Thioacetyl Chloride
CAS No.	52998-13-7
Molecular Formula	C7H6ClNOS
Molecular Weight	187.64 g/mol
Synonyms	2-Chloro-1-(pyridin-4-yl)ethanethione; 4-Pyridylthioacetyl Chloride; 4-Pyridylthioacetic Acid Chloride; (4-Pyridylthio)acetyl Chloride; 2-(Pyridin-4-ylthio)acetyl Chloride; 4-Pyridylmercaptoacetyl Chloride; α-Chloro-4-pyridyl Thioacetone; 52998-13-7
EINECS	Contact for details

Quality Control

Our 4-Pyridyl Thioacetyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.