Description

Locacorten-Vioform is a combination pharmaceutical compound primarily consisting of flumetasone pivalate and clioquinol. This product is a critical active pharmaceutical ingredient (API) used in the formulation of topical medications. It is essential for manufacturers developing dermatological treatments that require both anti-inflammatory and antimicrobial activity. The compound is supplied to pharmaceutical companies and contract manufacturing organizations (CMOs) globally for the production of prescription creams and ointments.

Application

• Primary API in the manufacture of topical corticosteroid-antibacterial combination creams and ointments.
• Key ingredient for dermatological formulations targeting inflammatory skin conditions with secondary bacterial or fungal infections.
• Used in pharmaceutical R&D for developing new topical drug delivery systems.
• Supplied to compounding pharmacies for specialized prescription preparations.
• Critical material for quality control and analytical laboratories as a reference standard.

Basic Information

Product Name	Locacorten-Vioform
CAS No.	52932-94-2
Molecular Formula	C24H28F2O6 • C9H5ClINO
Molecular Weight	Flumetasone pivalate: 474.48 g/mol; Clioquinol: 305.50 g/mol
Synonyms	Flumethasone Pivalate and Clioquinol; Flumetasone Pivalate with Clioquinol; Flumetasone 17-Pivalate and Iodochlorhydroxyquin; Locacorten-Vioform (Trade Name); Flumethasone 21-Pivalate and 5-Chloro-7-iodo-8-quinolinol; Flumetasone Pivalate and Iodochlorhydroxyquin; Flumethasone Pivalate and Clioquinol; Flumetasone Pivalate/Clioquinol Combination
EINECS	Contact for details

Quality Control

Our Locacorten-Vioform is manufactured under strict quality management systems. Every batch is tested to ensure it meets high-purity standards suitable for pharmaceutical use. We provide comprehensive Certificates of Analysis (COA) that detail identity, purity, and impurity profiles, referencing pharmacopeial methods where applicable. Our commitment to GMP compliance and supply chain traceability ensures reliability for critical manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	98.0% - 102.0% (Total combined)
Assay of Flumetasone Pivalate	Complies
Assay of Clioquinol	Complies
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.