Description

Cholesteryl Hemisuccinate Morpholine is a high-purity, functionalized cholesterol derivative widely used as a key intermediate in advanced pharmaceutical and biochemical research. This compound is valued for its role in modifying the physicochemical properties of molecules, particularly in the development of drug delivery systems and lipid-based formulations. It serves as a critical building block for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors seeking to enhance solubility, stability, and bioavailability.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Lipid Nanoparticle (LNP) Formulation: Used in the development and optimization of lipid-based delivery systems for mRNA, siRNA, and other nucleic acid therapeutics.
• Biomembrane Research: Serves as a model compound or a functional component in studies of membrane fluidity, structure, and cholesterol dynamics.
• Cosmetic & Dermatological Actives: Employed in the formulation of high-end skincare products for its potential stabilizing and delivery-enhancing properties.
• Bioconjugation & Linker Chemistry: The reactive succinate and morpholine groups facilitate its use as a linker for attaching therapeutic agents to carriers or surfaces.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Cholesteryl Hemisuccinate Morpholine
CAS No.	52910-93-7
Molecular Formula	C36H61NO5
Molecular Weight	587.88 g/mol
Synonyms	Cholesteryl Hemisuccinate Morpholine Salt; 3β-[(3-Carboxy-1-oxopropoxy)cholest-5-en-24-yl] Morpholine; Morpholine Cholesteryl Hemisuccinate; CHEMS-Morpholine; Cholesterol Hemisuccinate Morpholine Salt; NSC 357753; Cholest-5-en-3β-ol, 3-hemisuccinate, compound with morpholine
EINECS	Contact for details

Quality Control

Our Cholesteryl Hemisuccinate Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.