Description

1,5-Bis(Trimethylsilyl)-1H-Pyrazole CAS NO 52805-96-6 is a specialized organosilicon compound featuring a pyrazole ring protected by two trimethylsilyl groups. This functionalization makes it a valuable silylating agent and versatile building block in advanced organic synthesis, particularly for the protection of sensitive nitrogen-containing heterocycles. It is primarily utilized by pharmaceutical, agrochemical, and advanced materials researchers and manufacturers for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those containing pyrazole or other nitrogen heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Silylating Agent: Protects reactive NH groups in heterocyclic chemistry, enabling subsequent synthetic transformations that would otherwise be incompatible.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and material science.
• Organic Electronics: Potential precursor in the development of organic semiconductors and light-emitting materials.
• Academic & Industrial R&D: A critical reagent for method development and exploratory synthesis in organic and medicinal chemistry laboratories.

Basic Information

Product Name	1,5-Bis(Trimethylsilyl)-1H-Pyrazole
CAS No.	52805-96-6
Molecular Formula	C9H22N2Si2
Molecular Weight	214.46 g/mol
Synonyms	1H-Pyrazole, 1,5-bis(trimethylsilyl)-; 1,5-Bis(trimethylsilyl)pyrazole; Bis(trimethylsilyl)pyrazole; 1,5-Di(trimethylsilyl)-1H-pyrazole; 1,5-Bis(trimethylsilyl)pyrazole; 1,5-BTSP; Pyrazole, 1,5-bis(trimethylsilyl)-
EINECS	Contact for details

Quality Control

Our 1,5-Bis(Trimethylsilyl)-1H-Pyrazole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.