Description

Methylenomycin A CAS NO 52775-76-5 is a potent, naturally occurring antibiotic compound belonging to the cyclopentanoid class. It serves as a critical tool in biochemical and microbiological research, particularly for studying antibiotic resistance mechanisms and bacterial cell wall biosynthesis. This product is essential for pharmaceutical R&D laboratories, academic institutions, and biotechnology companies engaged in the discovery and development of novel antimicrobial agents.

Application

• Antimicrobial Research: Used as a reference standard and active agent in studies targeting Gram-positive bacteria and mycobacteria.
• Mechanism of Action Studies: A key compound for investigating the inhibition of bacterial cell wall synthesis and related resistance pathways.
• Pharmaceutical Development: Serves as a lead compound or biochemical probe in the discovery of new antibiotic classes.
• Microbiological Assays: Employed in agar diffusion tests, minimum inhibitory concentration (MIC) determinations, and other in vitro susceptibility testing.
• Biochemical Pathway Analysis: Utilized to elucidate biosynthetic pathways in Streptomyces and other antibiotic-producing microorganisms.
• Academic & Educational Use: A valuable teaching tool in advanced university courses covering medicinal chemistry and microbiology.

Basic Information

Item	Detail
Product Name	Methylenomycin A
CAS No.	52775-76-5
Molecular Formula	C12H16O4
Molecular Weight	224.25 g/mol
Synonyms	Methylenomycin; Antibiotic SS-228Y; 2,4-Cyclopentadiene-1-acetic acid, 5-(1-hydroxyethyl)-2-methylene-, γ-lactone; SS-228Y; 5-(1-Hydroxyethyl)-2-methylidene-2,4-cyclopentadien-1-acetic acid γ-lactone
EINECS	Contact for details

Quality Control

Our Methylenomycin A is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, spectroscopic identification (NMR, IR, MS), and determination of biological activity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic and should be kept under an inert atmosphere in a desiccated environment. Allow the vial to equilibrate to room temperature in a dry atmosphere before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Biological Activity (MIC)	Reported

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.