Description

4-Pyrimidinecarbonyl Chloride, 2,6-Dimethoxy- (9Ci) is a highly reactive and versatile acyl chloride derivative used as a critical building block in advanced organic synthesis. Its primary value lies in enabling the efficient introduction of the 2,6-dimethoxypyrimidine-4-carbonyl moiety into target molecules, a key step in creating complex heterocyclic compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides containing pyrimidine scaffolds.
• Ligand and Material Science: Serves as a precursor for creating specialized ligands used in catalysis and functional materials.
• Peptide Mimetics and Bioconjugation: Facilitates the acylation of amines in peptides or biomolecules to create conjugates for biological studies.
• Custom Synthesis and R&D: A vital reagent for contract research organizations (CROs) and academic labs exploring new chemical entities.

Basic Information

Item	Detail
Product Name	4-Pyrimidinecarbonyl Chloride, 2,6-Dimethoxy- (9Ci)
CAS No.	52759-24-7
Molecular Formula	C7H7ClN2O3
Molecular Weight	202.60 g/mol
Synonyms	2,6-Dimethoxypyrimidine-4-carbonyl chloride; 2,6-Dimethoxy-4-pyrimidinecarbonyl chloride; 4-Carboxy-2,6-dimethoxypyrimidine chloride; 2,6-Dimethoxy-4-pyrimidine carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 4-Pyrimidinecarbonyl Chloride, 2,6-Dimethoxy- (9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.