Description

Ethyl 3,7,12-Trioxo-5Betacholan-24-Oate is a high-purity synthetic bile acid derivative, specifically an ethyl ester of a triketo-cholanic acid. This compound is valued as a critical advanced pharmaceutical intermediate and a versatile research-grade biochemical for probing metabolic pathways. It is primarily sought by manufacturers and research institutions in the pharmaceutical, biochemical research, and fine chemical synthesis sectors for developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of steroid-based drugs and novel therapeutic agents targeting liver and metabolic functions.
• Biochemical Research: Used as a reference standard or probe in studies of bile acid metabolism, liver physiology, and nuclear receptor (e.g., FXR) signaling pathways.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for the preparation of more complex steroid derivatives and specialized organic molecules.
• Reference Standard: High-purity grade suitable for use as an analytical standard in quality control (QC) and research laboratory settings.
• Metabolic Pathway Studies: Investigational compound for in vitro and in vivo research into cholesterol catabolism and bile acid biosynthesis.

Basic Information

Item	Details
Product Name	Ethyl 3,7,12-Trioxo-5Betacholan-24-Oate
CAS No.	52718-49-7
Molecular Formula	C₂₆H₃₈O₅
Molecular Weight	430.58 g/mol
Synonyms	Ethyl 3,7,12-trioxo-5β-cholan-24-oate; 5β-Cholan-24-oic acid, 3,7,12-trioxo-, ethyl ester; Ethyl 3,7,12-triketo-5β-cholanate; Ethyl 3,7,12-trioxocholanate; Ethyl triketocholanate; 5β-Cholanic acid-3,7,12-trione ethyl ester; Ethyl 3,7,12-trioxo-5β-cholanate
EINECS	Contact for details

Quality Control

Our Ethyl 3,7,12-Trioxo-5Betacholan-24-Oate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting research and pharmaceutical-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.