Description

(2,5-Dimethoxyphenyl)Acetyl Chloride is a versatile and reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the (2,5-dimethoxyphenyl)acetyl moiety, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for research chemists and process development teams in the pharmaceutical, agrochemical, and material science industries seeking to develop new active compounds and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) agents and other therapeutic molecules.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators that require specific aromatic substitution patterns.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Material Science: Employed to synthesize monomers or functionalize polymers, imparting specific electronic or photophysical properties to advanced materials.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical reactions and constructing complex heterocyclic compounds.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	(2,5-Dimethoxyphenyl)Acetyl Chloride
CAS No.	52711-92-9
Molecular Formula	C10H11ClO3
Molecular Weight	214.65 g/mol
Synonyms	2-(2,5-Dimethoxyphenyl)acetyl chloride; 2,5-Dimethoxyphenacetyl chloride; (2,5-Dimethoxybenzene)acetyl chloride; α-Chloro-2,5-dimethoxyacetophenone; 2,5-Dimethoxyphenylacetic acid chloride; 52711-92-9; 2-(2,5-Dimethoxyphenyl)-2-oxoethyl chloride
EINECS	Contact for details

Quality Control

Our (2,5-Dimethoxyphenyl)Acetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solubility	Soluble in common organic solvents (e.g., DCM, THF, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.