Description

12β-Acetoxy-3β,8,14β,20-Tetrahydroxypregn-5-En-1-One CAS NO 52665-66-4 is a high-purity, multi-functional pregnane derivative, a key intermediate in the synthesis of complex steroid-based pharmaceuticals. Its value lies in providing a versatile and reliable building block for research and development, enabling the creation of novel therapeutic agents. This compound is essential for pharmaceutical manufacturers and research institutions focused on developing new drugs in areas such as endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of specialized steroid drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for the design, synthesis, and biological evaluation of new steroid analogs with potential therapeutic activity.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating steroid biosynthesis pathways, enzyme inhibition, and receptor binding mechanisms.

Basic Information

Product Name	12β-Acetoxy-3β,8,14β,20-Tetrahydroxypregn-5-En-1-One
CAS No.	52665-66-4
Molecular Formula	C23H34O7
Molecular Weight	422.52 g/mol
Synonyms	12β-Acetoxy-3β,8β,14β,20β-tetrahydroxypregn-5-en-1-one; 1-Oxo-12β-acetoxy-3β,8β,14β,20β-tetrahydroxypregn-5-ene; Pregn-5-ene-1,3,8,14,20-pentol, 12-acetate, (3β,8β,12β,14β,20β)-; 12β-Acetoxyprednisolone derivative; Steroid intermediate 52665-66-4
EINECS	Contact for details

Quality Control

Our 12β-Acetoxy-3β,8,14β,20-Tetrahydroxypregn-5-En-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.