Description

2-Isothiocyanatopyridine is a versatile heterocyclic building block characterized by its reactive isothiocyanate functional group. This compound is of significant value in organic synthesis, particularly for the formation of thiourea derivatives and as a key intermediate in the development of pharmaceuticals and agrochemicals. It is primarily sought by research institutions and industrial manufacturers in the life sciences sector for applications in medicinal chemistry, material science, and as a coupling agent.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly those targeting kinase inhibition and other therapeutic pathways.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its reactivity to create bioactive molecules.
• Material Science: Serves as a functionalization agent for modifying polymer surfaces or creating novel organic frameworks with specific properties.
• Bioconjugation & Labeling: Employed in biochemical research to label proteins, peptides, or other biomolecules via reaction with amine groups.
• Ligand Synthesis: Acts as a precursor for creating complex ligands used in catalysis and coordination chemistry.
• Chemical Research: A valuable reagent for academic and industrial R&D in heterocyclic and organosulfur chemistry.

Basic Information

Product Name	2-Isothiocyanatopyridine
CAS No.	52648-45-0
Molecular Formula	C6H4N2S
Molecular Weight	136.17 g/mol
Synonyms	2-Pyridyl isothiocyanate; Isothiocyanic acid, 2-pyridyl ester; 2-Pyridinyl isothiocyanate; Pyridine-2-isothiocyanate; 2-Pyridyl mustard oil; 2-Isothiocyanatopyridine; 2-Pyridylisothiocyanate; 2-PITC
EINECS	Contact for details

Quality Control

Our 2-Isothiocyanatopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and industrial-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.