Description

Quinoline, 2-[(Trimethylsilyl)Oxy]- (9Ci) CAS NO 52523-31-6 is a specialized organosilicon derivative of quinoline, serving as a valuable protected intermediate or reagent in advanced synthetic chemistry. Its core value lies in enabling complex molecular transformations, particularly in the synthesis of pharmaceuticals and fine chemicals, by offering a silyl-protected hydroxyl group. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity, functionalized building blocks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those containing functionalized quinoline scaffolds.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and pesticides.
• Material Science Research: Acts as a precursor or modifying agent in the development of organic electronic materials and advanced polymers.
• Organic Synthesis Reagent: Employed as a protected synthon in multi-step synthetic routes, facilitating reactions that are sensitive to free hydroxyl groups.
• Catalyst Ligand Preparation: Utilized in the development of novel ligand systems for catalytic applications.
• Academic & R&D Laboratories: Serves as a critical reagent for methodological development and exploratory chemistry in university and corporate research settings.

Basic Information

Product Name	Quinoline, 2-[(Trimethylsilyl)Oxy]- (9Ci)
CAS No.	52523-31-6
Molecular Formula	C12H17NOSi
Molecular Weight	219.35 g/mol
Synonyms	2-(Trimethylsiloxy)quinoline; 2-Quinolinol, trimethylsilyl ether; 2-(Trimethylsilyloxy)quinoline; 2-Hydroxyquinoline trimethylsilyl ether; 2-OTMS-Quinoline; Quinolin-2-yloxytrimethylsilane; 2-Quinolyloxytrimethylsilane; 2-(Trimethylsilyl)oxyquinoline
EINECS	Contact for details

Quality Control

Our Quinoline, 2-[(Trimethylsilyl)Oxy]- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity against established specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.