Description

1,8-Naphthyridine-3-Carbonyl Chloride,1-Ethyl-1,4-Dihydro-7-Methyl-4-Oxo is a high-purity, reactive chemical intermediate belonging to the naphthyridine class of heterocyclic compounds. This compound matters as a critical building block for the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antibacterial and antiviral agents, leveraging the naphthyridine core's biological activity.
• Agrochemical Research: Used to develop new active ingredients for crop protection products, such as herbicides and fungicides.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex heterocyclic compounds in custom synthesis and contract manufacturing.
• Material Science: Potential intermediate for the development of organic semiconductors, ligands for metal complexes, or specialty polymers.
• Academic & Institutional Research: Utilized in chemical biology and medicinal chemistry programs for studying structure-activity relationships (SAR).

Basic Information

Product Name	1,8-Naphthyridine-3-Carbonyl Chloride,1-Ethyl-1,4-Dihydro-7-Methyl-4-Oxo
CAS No.	52377-28-3
Molecular Formula	C13H13ClN2O2
Molecular Weight	264.71 g/mol
Synonyms	1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carbonyl chloride; 1-Ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid chloride; 3-Carboxy-1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine chloride; 1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carbonyl chloride; ENMD-1186 intermediate; 1,8-Naphthyridine-3-carbonyl chloride derivative
EINECS	Contact for details

Quality Control

Our 1,8-Naphthyridine-3-Carbonyl Chloride,1-Ethyl-1,4-Dihydro-7-Methyl-4-Oxo is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.