Description

Pregn-4-Ene-3,20-Dione, 6-Methyl-17-(1-Oxopropoxy)-, (6.Alpha.)- is a high-purity synthetic steroid derivative, also known by its CAS number 52358-60-8. This compound is a critical advanced intermediate in the synthesis of potent pharmaceutical actives, offering a reliable building block for complex molecular architectures. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of specialized steroid-based therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent glucocorticoids and other specialized steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry research for exploring new therapeutic agents, structure-activity relationship (SAR) studies, and metabolic pathway investigations.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of steroid drugs.

Basic Information

Product Name	Pregn-4-Ene-3,20-Dione, 6-Methyl-17-(1-Oxopropoxy)-, (6.Alpha.)-
CAS No.	52358-60-8
Molecular Formula	C24H34O4
Molecular Weight	386.53 g/mol
Synonyms	6α-Methyl-17-propionyloxyprogesterone; 6α-Methyl-17α-propionyloxyprogesterone; 6α-Methyl-17α-hydroxyprogesterone 17-propionate; 6α-Methyl-17α-propionyloxy-4-pregnene-3,20-dione; 6-Methyl-17-(1-oxopropoxy)pregn-4-ene-3,20-dione, (6α)-; 17α-Propionyloxy-6α-methylprogesterone; 6α-Methyl-17α-propionyloxyprogesterone; 6α-Methyl-17-propionyloxyprogesterone
EINECS	Contact for details

Quality Control

Our Pregn-4-Ene-3,20-Dione, 6-Methyl-17-(1-Oxopropoxy)-, (6.Alpha.) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.