Description

Dimethyl-2-Oxo-3-Phenylpropyl Phosphonate, 98 % is a high-purity organophosphorus compound that serves as a versatile building block in advanced organic synthesis. Its primary value lies in its role as a key reagent for the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective formation of α,β-unsaturated carbonyl compounds. This makes it an essential material for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A critical reagent for constructing α,β-unsaturated ketones and esters, which are common scaffolds in active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the synthesis of complex molecules for crop protection agents, including fungicides and herbicides.
• Fine Chemical Manufacturing: Enables the production of specialty chemicals, flavors, and fragrances through precise olefination reactions.
• Academic & Industrial R&D: A staple reagent in laboratory-scale research for method development and the synthesis of novel organic compounds.
• Material Science Precursor: Potential use in synthesizing organic ligands or monomers for advanced polymeric materials.

Basic Information

Product Name	Dimethyl-2-Oxo-3-Phenylpropyl Phosphonate, 98 %
CAS No.	52343-38-1
Molecular Formula	C₁₁H₁₅O₄P
Molecular Weight	242.21 g/mol
Synonyms	Dimethyl (2-oxo-3-phenylpropyl)phosphonate; (2-Oxo-3-phenylpropyl)phosphonic acid dimethyl ester; 3-Phenyl-2-oxopropylphosphonic acid dimethyl ester; Benzylacetone phosphonate; HWE Reagent for benzylidene acetone synthesis; Phosphonic acid, P-(2-oxo-3-phenylpropyl)-, dimethyl ester; Dimethyl (3-phenyl-2-oxopropyl)phosphonate
EINECS	Contact for details

Quality Control

Our Dimethyl-2-Oxo-3-Phenylpropyl Phosphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR, to ensure the specified 98% minimum purity and identity are met. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.