Description

(1R,4As)-Decahydro-1-[(R)-5-Hydroxy-3-Methylpentyl]-2,5,5,8Aβ-Tetramethyl-2α,3β-Naphthalenediol is a high-purity, stereochemically defined synthetic intermediate of significant commercial and research interest. Its precise molecular architecture makes it a valuable chiral building block for the synthesis of complex natural products and bioactive molecules. This compound is primarily sought by the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring high stereochemical fidelity and purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly in steroid and terpenoid-based drug discovery.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and plant growth regulators where biological activity is conformation-dependent.
• Fine Chemical Production: Serves as a sophisticated starting material or intermediate for custom synthesis and contract manufacturing organizations (CMOs).
• Academic & Industrial Research: Employed in chemical biology and medicinal chemistry research for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fragrance & Flavor Precursor: Potential use in the synthesis of complex, high-value odorants and flavoring agents due to its terpenoid backbone.
• Material Science: Investigated as a monomer or additive for creating polymers with specific chiral or structural properties.

Basic Information

Product Name	(1R,4As)-Decahydro-1-[(R)-5-Hydroxy-3-Methylpentyl]-2,5,5,8Aβ-Tetramethyl-2α,3β-Naphthalenediol
CAS No.	52329-57-4
Molecular Formula	C21H38O3
Molecular Weight	338.53 g/mol
Synonyms	1,2,3,4,4a,5,6,7,8,8a-Decahydro-1-[(R)-5-hydroxy-3-methylpentyl]-2,5,5,8a-tetramethyl-2,3-naphthalenediol; (1R,4aS)-Decahydro-1-[(R)-5-hydroxy-3-methylpentyl]-2,5,5,8a-tetramethyl-2,3-naphthalenediol; (2α,3β,4aR,8aR)-Decahydro-1-[(R)-5-hydroxy-3-methylpentyl]-2,5,5,8a-tetramethyl-2,3-naphthalenediol; A stereoisomer of Squalene Diol; Terpenoid Diol Intermediate; Chiral Naphthalenediol Derivative
EINECS	Contact for details

Quality Control

Our production of (1R,4As)-Decahydro-1-[(R)-5-Hydroxy-3-Methylpentyl]-2,5,5,8Aβ-Tetramethyl-2α,3β-Naphthalenediol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.