Description

3-Isoxazolecarbonyl Chloride, 5-Ethyl- (9Ci) is a versatile and reactive heterocyclic acid chloride building block used in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 5-ethylisoxazole-3-carbonyl moiety, a key structural motif in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly for creating amide and ester derivatives.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isoxazole ring contributes to biological activity.
• Chemical Research & Development: Serves as a crucial reagent in academic and industrial R&D for constructing complex heterocyclic molecules.
• Peptide Mimetics: Facilitates the creation of isoxazole-containing peptide analogs for probing biological pathways and drug discovery.
• Material Science Precursor: Potential use in synthesizing specialized polymers or ligands for catalytic systems.

Basic Information

Product Name	3-Isoxazolecarbonyl Chloride, 5-Ethyl- (9Ci)
CAS No.	52320-58-8
Molecular Formula	C6H6ClNO2
Molecular Weight	159.57 g/mol
Synonyms	5-Ethylisoxazole-3-carbonyl chloride; 5-Ethyl-3-isoxazolecarbonyl chloride; 5-Ethyl-1,2-oxazole-3-carbonyl chloride; 3-Carboxy-5-ethylisoxazole chloride; 5-Ethyl-3-isoxazolylcarbonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Isoxazolecarbonyl Chloride, 5-Ethyl- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.