Description

2-Methyl-Cyclopropanecarbonyl Chloride is a versatile and highly reactive organic intermediate, primarily valued for its role as a key acylating agent in the synthesis of complex molecules. Its unique cyclopropane ring structure imparts significant steric and electronic properties, making it a critical building block for introducing the 2-methylcyclopropylcarbonyl moiety into target compounds. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a sterically constrained cyclopropane scaffold for biological activity.
• Agrochemical Synthesis: Used in the manufacturing of advanced pesticides and herbicides, where the methylcyclopropane group can enhance stability and efficacy.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Polymer Modification: Employed to introduce functional cyclopropane groups into polymer chains, altering physical properties like toughness and thermal stability.
• Fine Chemical Production: A crucial reagent for the preparation of esters, amides, and ketones bearing the 2-methylcyclopropyl group in multi-step synthetic routes.
• Material Science Research: Utilized in the development of novel organic electronic materials and liquid crystals due to its rigid molecular geometry.

Basic Information

Item	Details
Product Name	2-Methyl-Cyclopropanecarbonyl Chloride
CAS No.	52194-65-7
Molecular Formula	C5H7ClO
Molecular Weight	118.56 g/mol
Synonyms	2-Methylcyclopropanecarbonyl chloride; 2-Methylcyclopropanecarboxylic acid chloride; 2-Methylcyclopropylcarbonyl chloride; α-Methylcyclopropanecarbonyl chloride; (2-Methylcyclopropyl)carbonyl chloride; 2-Methylcyclopropanecarboxyl chloride; Cyclopropanecarbonyl chloride, 2-methyl-; 52194-65-7
EINECS	Contact for details

Quality Control

Our 2-Methyl-Cyclopropanecarbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopic methods, to confirm identity and quantify purity and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.