Description

2-Iodo-5-Methylbenzoyl Chloride is a versatile and highly reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 2-iodo-5-methylbenzoyl moiety into target molecules, facilitating the creation of complex chemical architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel compounds requiring specific halogenated aromatic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that leverage its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials with tailored electronic or photophysical properties.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Iodo-5-Methylbenzoyl Chloride
CAS No.	52107-96-7
Molecular Formula	C8H6ClIO
Molecular Weight	280.49 g/mol
Synonyms	5-Methyl-2-iodobenzoyl chloride; 2-Iodo-5-methylbenzoic acid chloride; 2-Iodo-p-toluoyl chloride; 2-Iodo-5-methyl-benzoylchlorid; Benzoic acid, 2-iodo-5-methyl-, chloride; 52107-96-7; 2-Iodo-5-methylbenzoylchloride
EINECS	Contact for details

Quality Control

Our 2-Iodo-5-Methylbenzoyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, identity confirmation by FT-IR and NMR spectroscopy, and control of key impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.