Description

Benzenepropanoyl Chloride, 4-Chloro- is a specialized aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its high reactivity, enabling efficient acylation reactions to introduce the 4-chlorohydrocinnamoyl moiety into target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require the 4-chlorophenylpropionyl structural motif.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to functionalize polymers, introducing chlorinated aromatic groups to alter material properties like thermal stability and solubility.
• Peptide Mimetics & Bio-conjugation: Useful in medicinal chemistry for constructing peptide analogs and for bio-conjugation techniques in probe and drug delivery system development.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	Benzenepropanoyl Chloride, 4-Chloro-
CAS No.	52085-96-8
Molecular Formula	C9H8Cl2O
Molecular Weight	203.06 g/mol
Synonyms	4-Chlorohydrocinnamoyl Chloride; 3-(4-Chlorophenyl)propionyl Chloride; 4-Chloro-β-phenylpropionyl Chloride; (4-Chlorophenyl)propanoic Acid Chloride; 3-(4-Chlorophenyl)propanoyl Chloride; γ-(4-Chlorophenyl)propionyl Chloride; Benzenepropanoyl chloride, 4-chloro-; 52085-96-8
EINECS	Contact for details

Quality Control

Our Benzenepropanoyl Chloride, 4-Chloro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts vigorously with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.