Description

2,3-Dihydro-5-Fluoro-1H-Inden-1-Ol CAS NO 52085-92-4 is a fluorinated indanol derivative, a versatile chiral building block and key synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular scaffold, which is crucial for constructing complex pharmacologically active molecules with high stereochemical purity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Chiral Synthesis: Used as a starting material or resolving agent for the preparation of enantiomerically pure compounds in asymmetric synthesis.
• Agrochemical Research: Acts as a building block for developing new fluorinated pesticides and herbicides, leveraging the fluorine atom's ability to modulate biological activity and stability.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Academic & R&D: Employed in methodological studies and chemical research exploring new fluorination reactions and indane chemistry.

Basic Information

Product Name	2,3-Dihydro-5-Fluoro-1H-Inden-1-Ol
CAS No.	52085-92-4
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	5-Fluoro-1-indanol; 5-Fluoroindan-1-ol; (5-Fluoro-2,3-dihydro-1H-inden-1-ol); 5-Fluoro-2,3-dihydro-1H-inden-1-one (reduction product); 1-Hydroxy-5-fluoroindane; 5-Fluoro-1-hydroxyindane; FLUOROINDANOL; 52085-92-4
EINECS	Contact for details

Quality Control

Our production of 2,3-Dihydro-5-Fluoro-1H-Inden-1-Ol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high-purity standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.