Description

Pyridine, 5-Isothiocyanato-2-Methoxy- is a specialized heterocyclic building block featuring both a methoxy and a reactive isothiocyanate functional group. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry, where it is used to introduce thiourea moieties via nucleophilic addition reactions.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially those targeting kinase inhibition or requiring thiourea linkages.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that utilize the pyridine-thiourea scaffold for bioactivity.
• Bioconjugation & Labeling Reagent: The reactive isothiocyanate group allows for covalent attachment to amines in proteins, peptides, or other biomolecules for labeling and probe development.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of advanced polymers and functional materials.
• Chemical Biology Tool: Employed in the design and synthesis of molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	Pyridine, 5-Isothiocyanato-2-Methoxy-
CAS No.	52023-93-5
Molecular Formula	C8H6N2OS
Molecular Weight	178.21 g/mol
Synonyms	5-Isothiocyanato-2-methoxypyridine; 2-Methoxy-5-isothiocyanatopyridine; 2-Methoxypyridin-5-yl isothiocyanate; 5-Isothiocyanato-2-pyridinol methyl ether; 2-Pyridinol, 5-isothiocyanato-, methyl ether
EINECS	Contact for details

Quality Control

Our production of Pyridine, 5-Isothiocyanato-2-Methoxy- adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. Each lot is characterized by modern analytical techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.