Description

2'-Tfa-Nh-Du CAS NO 51989-21-0 is a specialized, high-purity chemical intermediate primarily used in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is essential for researchers and production chemists in the pharmaceutical, agrochemical, and biotechnology sectors who require reliable, high-quality intermediates for peptide and nucleoside-related synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral and anticancer drug candidates.
• Peptide Synthesis: Used as a protected amino acid derivative or coupling agent in solid-phase and solution-phase peptide chemistry.
• Nucleoside & Nucleotide Chemistry: Serves as a modified building block for the research and production of novel nucleoside analogs.
• Bioconjugation: Employed in the labeling and modification of biomolecules for diagnostic and research applications.
• Fine Chemical Production: Acts as a versatile intermediate in the custom synthesis of complex organic compounds for various high-value industries.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in chemical research laboratories.

Basic Information

Item	Details
Product Name	2'-Tfa-Nh-Du
CAS No.	51989-21-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2'-TFA-NH-dU; 5'-O-DMT-2'-deoxy-2'-fluoro-5-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; 2'-Deoxy-2'-fluoro-5-methyluridine derivative; 2'-F-5-Me-dU TFA amine; 2'-Fluoro-5-methyluridine TFA protected intermediate; 5-Methyl-2'-fluoro-2'-deoxyuridine TFA amine; CAS 51989-21-0
EINECS	Contact for details

Quality Control

Every batch of 2'-Tfa-Nh-Du is produced and tested under strict quality management protocols to ensure consistency and purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC), identity confirmation, and impurity profiles. Our quality systems are designed to meet the stringent requirements of cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.