Description

8-Isothiocyanatopyrene-1,3,6-Trisulfonic Acid Trisodium Salt is a highly reactive, water-soluble fluorescent labeling reagent derived from pyrene. This compound matters for its ability to form stable thiourea bonds with primary amines, making it an essential tool for the covalent tagging of biomolecules such as proteins, peptides, and amino-modified surfaces. It is primarily needed by researchers and manufacturers in the life sciences, diagnostics, and analytical chemistry sectors for applications in fluorescence detection, bio-conjugation, and sensor development.

Application

• Fluorescent Labeling of Biomolecules: Covalent conjugation to proteins, antibodies, and peptides for fluorescence microscopy, immunoassays, and flow cytometry.
• Bio-conjugation Chemistry: Used as a key reagent for attaching fluorescent probes to amino-functionalized nanoparticles, polymers, and solid supports.
• Sensor Development: Employed in the fabrication of fluorescent chemical sensors and biosensors for detecting various analytes.
• Capillary Electrophoresis and HPLC: Acts as a derivatization agent for the sensitive detection of amines and amino acids in separation sciences.
• Material Science: Modification of surface properties for creating functionalized materials with specific optical characteristics.
• Diagnostic Reagent Manufacturing: A component in the synthesis of fluorescent tags for in vitro diagnostic (IVD) kits and reagents.

Basic Information

Product Name	8-Isothiocyanatopyrene-1,3,6-Trisulfonic Acid Trisodium Salt
CAS No.	51987-57-6
Molecular Formula	C21H10NNa3O9S4
Molecular Weight	665.53 g/mol
Synonyms	Pyranine isothiocyanate; 1,3,6-Pyrenetrisulfonic acid, 8-isothiocyanato-, trisodium salt; 8-Isothiocyanato-1,3,6-pyrenetrisulfonic acid trisodium salt; Trisodium 8-isothiocyanatopyrene-1,3,6-trisulfonate; HPTS isothiocyanate; Pyrene trisulfonate isothiocyanate; Fluorescent isothiocyanate dye; Reactive pyrene dye
EINECS	Contact for details

Quality Control

Our 8-Isothiocyanatopyrene-1,3,6-Trisulfonic Acid Trisodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under desiccant or inert atmosphere when not in use to prevent degradation. For long-term stability, store frozen at -20°C.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by elemental analysis)
Water Content	≤ 5.0% (KF)
Solubility	Freely soluble in water, DMSO
Fluorescence	Characteristic emission in aqueous solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.