Description

5,6-Dihydro-3,5-Dimethyl-3'-O,5'-o-Dimethylthymidine is a chemically modified nucleoside derivative, primarily utilized as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. Its value lies in its role as a building block for the development of novel antiviral and anticancer agents, particularly in the creation of modified oligonucleotides and prodrugs. This high-purity compound is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and therapeutic innovation.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of nucleoside-based antiviral drugs and anticancer therapeutics.
• Biochemical Research: Used as a modified building block in oligonucleotide synthesis for studying DNA/RNA structure, function, and for developing antisense or siRNA technologies.
• Prodrug Development: Serves as a precursor in the design of prodrugs aimed at improving the bioavailability and targeted delivery of active nucleoside analogs.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized chemical libraries and reference standards.
• Academic Research: A valuable tool in university and institutional labs for exploring novel pathways in medicinal chemistry and chemical biology.

Basic Information

Item	Details
Product Name	5,6-Dihydro-3,5-Dimethyl-3'-O,5'-o-Dimethylthymidine
CAS No.	51844-39-4
Molecular Formula	C14H22N2O5
Molecular Weight	298.34 g/mol
Synonyms	3',5'-Di-O-methyl-5,6-dihydro-3,5-dimethylthymidine; 3'-O,5'-O-Dimethyl-5,6-dihydro-3,5-dimethylthymidine; Dihydrodimethylthymidine dimethyl ether; Modified Thymidine Derivative; 5,6-Dihydrothymidine dimethyl ether; Nucleoside Intermediate 51844-39-4
EINECS	Contact for details

Quality Control

Our 5,6-Dihydro-3,5-Dimethyl-3'-O,5'-o-Dimethylthymidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements. Specifications can be tailored to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.