Description

4H-Thiopyran-3-Carbonyl Chloride, 4-Oxo- (9Ci) is a specialized heterocyclic building block featuring a reactive carbonyl chloride group, making it a critical intermediate for advanced organic synthesis. Its core value lies in enabling the efficient introduction of the thiopyran scaffold into target molecules, which is essential for developing compounds with specific electronic and structural properties. This high-purity intermediate is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the thiopyran moiety can contribute to biological activity.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic libraries for high-throughput screening.
• Ligand & Catalyst Development: Utilized to create novel sulfur-containing ligands for transition metal catalysis and coordination chemistry.

Basic Information

Product Name	4H-Thiopyran-3-Carbonyl Chloride, 4-Oxo- (9Ci)
CAS No.	51727-16-3
Molecular Formula	C6H3ClO2S
Molecular Weight	174.60 g/mol
Synonyms	4-Oxo-4H-thiopyran-3-carbonyl chloride; 3-Chlorocarbonyl-4H-thiopyran-4-one; 4H-Thiopyran-4-one, 3-carbonyl chloride; 4-Oxothiopyran-3-carbonyl chloride; 3-Carboxythiopyran-4-one chloride; 4-Oxo-4H-thiopyran-3-carboxylic acid chloride; 3-(Chlorocarbonyl)-4H-thiopyran-4-one
EINECS	Contact for details

Quality Control

Our production of 4H-Thiopyran-3-Carbonyl Chloride, 4-Oxo- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All material is characterized by modern analytical techniques including NMR, HPLC, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.