Description

4-Sulphamoylbenzoyl Chloride is a key sulfonamide-based acid chloride intermediate essential for synthesizing active pharmaceutical ingredients (APIs) and fine chemicals. Its reactive carbonyl chloride group enables efficient amide bond formation, making it a critical building block for medicinal chemistry and advanced material science. This high-purity compound is primarily utilized by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers developing sulfonamide-derived compounds.

Application

• Pharmaceutical Intermediate: Core building block for the synthesis of diuretic and antihypertensive sulfonamide drugs.
• Agrochemical Synthesis: Used in creating sulfonylurea-based herbicides and fungicides.
• Dye & Pigment Manufacturing: Intermediate for producing sulfonated azo dyes and colorants.
• Polymer Chemistry: Monomer for introducing sulfonamide functional groups into specialty polymers.
• Research & Development: Key reagent in organic synthesis for academic and industrial research projects.
• Chemical Derivatization: Used to prepare analytical standards and biochemical probes.

Basic Information

Product Name	4-Sulphamoylbenzoyl Chloride
CAS No.	51594-97-9
Molecular Formula	C7H6ClNO3S
Molecular Weight	219.64 g/mol
Synonyms	4-Sulfamoylbenzoyl chloride; p-Sulfamoylbenzoyl chloride; Benzoic acid, 4-(aminosulfonyl)-, chloride; 4-Carboxybenzenesulfonamide chloride; 4-(Chlorocarbonyl)benzenesulfonamide; NSC 163082; p-Carboxybenzenesulfonamide chloride
EINECS	Contact for details

Quality Control

Our 4-Sulphamoylbenzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR for identification, and titration for assay to ensure it meets exacting standards for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. Keep away from strong bases, oxidizing agents, and moisture. Due to its acid chloride nature and sensitivity to light and moisture, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158°C - 162°C
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.