Description

Cyclobutanecarbonyl Chloride, 2-Chloro-2,3,3-Trifluoro- (9Ci) CAS NO 51504-22-4 is a highly reactive fluorinated acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce the cyclobutane ring and trifluoromethyl groups into target molecules, significantly altering their physical and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used to construct advanced herbicides, fungicides, and insecticides where the cyclobutane and fluorine motifs enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated components in electronic display and lighting technologies.
• Polymer Modification: Employed to introduce fluorinated cyclobutane units into polymer backbones, improving chemical resistance and thermal properties.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and other acyl transfer reactions in complex molecule construction.
• Fluorine Chemistry Research: Valuable substrate for studying the reactivity of polyfluorinated carbocyclic systems in academic and industrial R&D settings.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 2-Chloro-2,3,3-Trifluoro- (9Ci)
CAS No.	51504-22-4
Molecular Formula	C5H3Cl2F3O
Molecular Weight	198.98 g/mol
Synonyms	2-Chloro-2,3,3-trifluorocyclobutanecarbonyl chloride; 2-Chloro-2,3,3-trifluoro-1-cyclobutanecarboxylic acid chloride; 2-Chloro-2,3,3-trifluorocyclobutane-1-carbonyl chloride; 1-Cyclobutanecarbonyl chloride, 2-chloro-2,3,3-trifluoro-; 51504-22-4; 2,3,3-Trifluoro-2-chlorocyclobutanecarboxylic acid chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed to confirm identity, purity, and impurity profile. Certificates of Analysis (COA) detailing specific results for purity (by GC or HPLC), water content (KF), and identity (IR, NMR) are available upon request. We adhere to cGMP principles for manufacturing and quality management where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis and degradation. Keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.