Description

4-Azidobutyric Acid Ethyl Ester is a versatile organic azide building block used in click chemistry and bioconjugation applications. Its value lies in its ability to participate in the Staudinger ligation and copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling the efficient and selective labeling of biomolecules and polymers. This compound is essential for researchers and manufacturers in pharmaceutical development, materials science, and chemical biology who require reliable, high-purity intermediates for advanced synthesis.

Application

• Bioconjugation Reagent: Used for site-specific labeling of proteins, antibodies, and oligonucleotides via click chemistry reactions.
• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of drug candidates, particularly those incorporating triazole linkages.
• Polymer Functionalization: Enables the modification of polymer backbones to introduce azide groups for subsequent cross-linking or grafting.
• Proteomics Research: Employed in activity-based protein profiling (ABPP) and the development of chemical probes for enzyme studies.
• Materials Science: Used to create functional surfaces, hydrogels, and smart materials with tailored chemical properties.
• Diagnostic Agent Synthesis: A precursor in the development of contrast agents and molecular imaging probes.

Basic Information

Product Name	4-Azidobutyric Acid Ethyl Ester
CAS No.	51453-79-3
Molecular Formula	C6H11N3O2
Molecular Weight	157.17 g/mol
Synonyms	Ethyl 4-Azidobutyrate; 4-Azidobutanoic Acid Ethyl Ester; Ethyl 4-Azidobutanoate; Azidobutyric Acid Ethyl Ester; Butanoic acid, 4-azido-, ethyl ester; Ethyl γ-azidobutyrate; γ-Azidobutyric Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 4-Azidobutyric Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, containers should be kept in opaque or amber glass and handled under subdued light. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.