Description

Cytosine 5-Hydroxysulfate is a chemically modified nucleoside derivative, specifically the 5-sulfate ester of cytosine. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or precursor in the synthesis of novel nucleoside analogs and antiviral agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the development of therapeutic compounds targeting viral infections and other diseases. The product is supplied with a focus on high purity and batch-to-batch consistency to support critical R&D and manufacturing processes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or modified nucleotide in enzymatic studies and metabolic pathway investigations.
• Antiviral Drug Development: Serves as a precursor for the development of potential therapeutic agents against DNA and RNA viruses.
• Proteomics & Genomics: Can be employed in the study of nucleic acid modifications and their biological functions.
• Fine Chemical Synthesis: Utilized in custom synthesis and the production of specialized, high-value chemical entities.
• Reference Standard: Serves as a certified reference material for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	Cytosine 5-Hydroxysulfate
CAS No.	51392-11-1
Molecular Formula	C4H5N3O5S
Molecular Weight	207.16 g/mol
Synonyms	5-Sulfocytosine; Cytosine 5-Sulfate; Cytosine 5-O-Sulfate; 4-Amino-2-oxo-1,2-dihydropyrimidin-5-yl hydrogen sulfate; 5-Sulfooxycytosine; 1H-Pyrimidin-2-one, 4-amino-5-(sulfooxy)-; Cytosine-5-yl sulfate
EINECS	Contact for details

Quality Control

Our Cytosine 5-Hydroxysulfate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material meets the high standards required for research and pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.