Description

Bis(p-Nitrophenyl) Azidophosphonate is a specialized organophosphorus compound characterized by its reactive azido and nitrophenyl groups. This unique structure makes it a valuable intermediate in advanced organic synthesis, particularly for the preparation of photoaffinity labeling reagents and cross-linking agents. It is primarily utilized by research institutions and industrial R&D departments focused on biochemistry, pharmaceutical development, and materials science.

Application

• Photoaffinity Labeling: A critical reagent for identifying and studying biological receptors and active sites in drug discovery.
• Cross-linking Agent: Used in polymer chemistry and bioconjugation to create stable covalent bonds between molecules.
• Chemical Biology Research: Serves as a key intermediate for synthesizing probes to investigate protein-ligand interactions and enzyme mechanisms.
• Pharmaceutical Intermediate: Employed in the synthesis of novel active pharmaceutical ingredients (APIs) and diagnostic agents.
• Materials Science: Used in the development of advanced polymeric materials with specific functional properties.

Basic Information

Product Name	Bis(p-Nitrophenyl) Azidophosphonate
CAS No.	51250-91-0
Molecular Formula	C₁₂H₈N₅O₆P
Molecular Weight	349.20 g/mol
Synonyms	Bis(4-nitrophenyl) azidophosphonate; Phosphonic acid, azido-, bis(4-nitrophenyl) ester; Azidobis(4-nitrophenyl)phosphonate; p-Nitrophenyl azidophosphonate; Azidophosphonic acid bis(4-nitrophenyl) ester; Photoaffinity labeling reagent
EINECS	Contact for details

Quality Control

Our Bis(p-Nitrophenyl) Azidophosphonate is manufactured under strict quality protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) due to its moisture-sensitive and easily oxidized nature. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (e.g., DMF, DMSO, acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.