Description

5'-o-Acetyl-2'-3'-Dideoxy-3'-Fluoro-Uridine is a chemically modified nucleoside analog, serving as a critical intermediate in the synthesis of more complex antiviral and anticancer agents. Its value lies in its precise molecular structure, which allows researchers to explore novel therapeutic pathways, particularly in the development of nucleoside-based pharmaceuticals. This high-purity building block is essential for pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and diagnostic probes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the research and development of novel therapeutics targeting viral polymerases.
• Oncology Research: Serves as a building block for potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Probe Synthesis: Utilized to create labeled or modified nucleotides for studying enzymatic mechanisms and cellular processes.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry and drug discovery programs.
• Process Development: Used in scaling up synthetic routes for the commercial manufacturing of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5'-o-Acetyl-2'-3'-Dideoxy-3'-Fluoro-Uridine
CAS No.	51247-09-7
Molecular Formula	C11H13FN2O5
Molecular Weight	272.23 g/mol
Synonyms	2',3'-Dideoxy-3'-fluoro-5'-O-acetyluridine; 3'-Fluoro-2',3'-dideoxy-5'-O-acetyluridine; 5'-O-Acetyl-3'-fluoro-2',3'-dideoxyuridine; 3'-FddUrd(Ac); 3'-Fluoro-5'-O-acetyl-2',3'-dideoxyuridine; 1-[(2R,5S)-5-(Acetyloxy)-2-(fluoromethyl)tetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5'-o-Acetyl-2'-3'-Dideoxy-3'-Fluoro-Uridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.