Description

2',3'-Dideoxy-3'-Fluorocytidine is a fluorinated nucleoside analogue of significant interest in pharmaceutical research and development. This compound is a key synthetic intermediate and a crucial building block for the creation of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and CDMOs engaged in the development of nucleoside-based drugs. The product is supplied with a high level of purity and batch-to-batch consistency to support critical research and manufacturing processes.

Application

• Pharmaceutical Intermediate: A vital precursor in the synthesis of more complex nucleoside analogues with potential therapeutic activity.
• Antiviral Drug Research: Used in the development and study of novel antiviral agents, particularly against retroviruses and other viral families.
• Anticancer Agent Development: Serves as a building block for creating nucleoside derivatives that target DNA synthesis in rapidly dividing cancer cells.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleic acid metabolism and related pathways.
• Pro-drug Synthesis: Utilized in the chemical modification and design of pro-drugs to improve the pharmacokinetic properties of active nucleoside drugs.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2',3'-Dideoxy-3'-Fluorocytidine
CAS No.	51246-79-8
Molecular Formula	C9H12FN3O3
Molecular Weight	229.21 g/mol
Synonyms	3'-Fluoro-2',3'-dideoxycytidine; 3'-F-ddC; 2',3'-Dideoxy-3'-fluorocytidine; 3'-Fluoro-ddC; 3'-F-2',3'-ddC; 4-Amino-1-((2R,5S)-5-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; β-3'-Fluoro-2',3'-dideoxycytidine
EINECS	Contact for details

Quality Control

Every batch of 2',3'-Dideoxy-3'-Fluorocytidine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and identity confirmation, meeting the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.