Description

Dermostatin B CAS NO 51141-40-3 is a high-purity pharmaceutical-grade antifungal compound. It is valued for its targeted efficacy against dermatological fungal infections, offering a critical active ingredient for advanced topical formulations. This product is essential for manufacturers in the pharmaceutical and advanced dermatological care sectors seeking reliable, high-quality raw materials for antifungal creams, ointments, and medicated powders.

Application

• Primary active ingredient in prescription and over-the-counter (OTC) topical antifungal creams and ointments.
• Formulation component for medicated powders and sprays targeting athlete's foot and other cutaneous mycoses.
• Use in veterinary dermatology products for the treatment of fungal skin infections in animals.
• Key intermediate in the synthesis of more complex antifungal agents and pharmaceutical research.
• Incorporation into specialized dermatological preparations for compounded medications.

Basic Information

Product Name	Dermostatin B
CAS No.	51141-40-3
Molecular Formula	C35H58NO8
Molecular Weight	620.84 g/mol
Synonyms	Dermostatin; Dermostatin B complex; Antibiotic A 246; A 246 Antibiotic; Filipin III; 5-[(1E,3E,5E,7E,9E,11E,13E,15E,17E,19E)-20-[(2R,3R,4S,5S,6R)-4-Amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-3,7,12,16-tetramethylicosa-1,3,5,7,9,11,13,15,17,19-decaen-1-yl]-2-methylbenzene-1,3-diol
EINECS	Contact for details

Quality Control

Our Dermostatin B is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can support compliance documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and potency.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Microbial Enumeration	Meets Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.