Description

2'-Azido-2'-Deoxycytidine is a chemically modified nucleoside analog, a critical building block in medicinal chemistry and biochemical research. Its unique azido functional group makes it an invaluable precursor for the synthesis of novel antiviral and anticancer agents via click chemistry. This high-purity intermediate is essential for pharmaceutical R&D laboratories and fine chemical manufacturers developing next-generation nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of experimental antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a modified substrate to study enzyme mechanisms, particularly DNA/RNA polymerases and kinases.
• Click Chemistry: The azido group enables efficient, site-specific conjugation with alkynes for bioconjugation and prodrug development.
• Antiviral Drug Development: Serves as a core scaffold for creating novel compounds targeting viral replication.
• Labeling and Probe Synthesis: Incorporated into oligonucleotides or other molecules for tracking and diagnostic applications.
• Academic & Industrial R&D: Fundamental material for exploring new therapeutic modalities in life sciences.

Basic Information

Product Name	2'-Azido-2'-Deoxycytidine
CAS No.	51034-68-5
Molecular Formula	C9H12N6O4
Molecular Weight	268.23 g/mol
Synonyms	2'-Azido-2'-deoxycytidine; 1-(2-Azido-2-deoxy-β-D-ribofuranosyl)cytosine; 2'-N3-2'-dC; Azidodeoxycytidine; 2'-Azido-2'-deoxycytidine; 2'-Azidocytidine; NSC 401005; 2'-Azido-2'-deoxycytidine (2'-N3-2'-dC)
EINECS	Contact for details

Quality Control

Our 2'-Azido-2'-Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive and should be handled under appropriate conditions to maintain purity. Keep container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.