Description

Benzeneacetyl Chloride, α-(Acetyloxy)-, (αs)- is a specialized chiral organic intermediate of significant synthetic utility. This compound matters for its role as a key building block in the production of enantiomerically pure pharmaceuticals and advanced agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system and cardiovascular drug research.
• Agrochemical Synthesis: Used in the production of advanced, optically active pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Serves as a versatile building block for creating complex molecules in custom synthesis and process development for specialty chemicals.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new asymmetric synthetic methodologies.
• Material Science Precursor: Potential use in the synthesis of chiral monomers for advanced polymeric materials with specific optical properties.

Basic Information

Product Name	Benzeneacetyl Chloride, α-(Acetyloxy)-, (αs)-
CAS No.	51019-44-4
Molecular Formula	C10H9ClO3
Molecular Weight	212.63 g/mol
Synonyms	(S)-(-)-α-Acetoxybenzeneacetyl chloride; (S)-O-Acetylmandelic acid chloride; (S)-2-Acetoxy-2-phenylacetyl chloride; (S)-α-Acetoxyphenylacetyl chloride; L-α-Acetoxybenzeneacetyl chloride; (2S)-2-Acetoxy-2-phenylacetyl chloride; Mandelic acid, α-acetoxy-, chloride, (S)-; (S)-(-)-α-Acetoxyphenylacetyl chloride
EINECS	Contact for details

Quality Control

Our Benzeneacetyl Chloride, α-(Acetyloxy)-, (αs)- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.