Description

α-Hydroxybenzeneacetyl Chloride is a specialized organic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its high reactivity, enabling efficient acylation and esterification reactions to construct complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), advanced intermediates, and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in constructing benzoyl and ester functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific acyl chloride chemistry.
• Fine Chemical Production: Acts as a versatile acylating agent for manufacturing dyes, pigments, and specialty polymers.
• Academic & Industrial R&D: Employed in research laboratories for method development and exploring new synthetic pathways in organic chemistry.
• Material Science: Potential use in the surface modification of materials and the synthesis of monomers for specialty resins.

Basic Information

Product Name	α-Hydroxybenzeneacetyl Chloride
CAS No.	50916-31-9
Molecular Formula	C8H7ClO2
Molecular Weight	170.59 g/mol
Synonyms	2-Hydroxyphenylacetyl chloride; (2-Hydroxyphenyl)acetyl chloride; o-Hydroxyphenylacetyl chloride; 2-Hydroxybenzeneacetyl chloride; Mandelic acid chloride, o-hydroxy-; α-Hydroxy-o-toluoyl chloride
EINECS	Contact for details

Quality Control

Our α-Hydroxybenzeneacetyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.