Description

3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-α-L-Mannopyranosyl)Oxy]-16β-Hydroxy-5β-Card-20(22)-Enolide is a high-purity, complex cardiac glycoside derivative with a specific glycosidic linkage. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of cardiotonic agents and their structure-activity relationships. It serves as a critical reference standard and intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in drug development.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic building block in the production of specialized cardiac therapeutics.
• Biochemical Research: Employed in pharmacological studies to investigate the mechanisms of action of cardiac glycosides on sodium-potassium ATPase pumps.
• Analytical Chemistry: Utilized as an analytical standard for HPLC, LC-MS, and NMR to quantify and identify related compounds in complex matrices.
• Preclinical Development: Applied in animal studies and in vitro assays to evaluate efficacy, pharmacokinetics, and toxicity profiles.

Basic Information

Product Name	3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-α-L-Mannopyranosyl)Oxy]-16β-Hydroxy-5β-Card-20(22)-Enolide
CAS No.	50906-57-5
Molecular Formula	C35H54O14
Molecular Weight	698.80 g/mol
Synonyms	16β-Hydroxygitoxin; Gitoxin 16'-acetate (related derivative); 3β-[(4-O-β-D-Glucopyranosyl-6-deoxy-α-L-mannopyranosyl)oxy]-16β-hydroxy-5β-card-20(22)-enolide; 16β-Hydroxy-3β-[(4-O-β-D-glucopyranosyl-6-deoxy-α-L-mannopyranosyl)oxy]-5β-card-20(22)-enolide; A cardiac glycoside aglycone derivative; Gitoxin isomer; 5β,14β-Card-20(22)-enolide, 3-[(6-deoxy-4-O-β-D-glucopyranosyl-α-L-mannopyranosyl)oxy]-16-hydroxy-, (3β,5β,16β)-
EINECS	Contact for details

Quality Control

Our 3β-[(4-o-β-D-Glucopyranosyl-6-Deoxy-α-L-Mannopyranosyl)Oxy]-16β-Hydroxy-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, chiral purity verification, and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, batch-to-batch consistency, and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. The container should be kept in a dry, cool, and well-ventilated area. For long-term storage, consider storing under inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.