Description

1-Chloroethyl Chloroformate is a highly reactive chloroformate ester, a key intermediate in organic synthesis. Its primary value lies in its ability to act as a versatile reagent for the introduction of the chloroethoxycarbonyl protecting group, facilitating complex chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the synthesis of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Key intermediate in the synthesis of pharmaceutical compounds, including prodrugs and active pharmaceutical ingredients (APIs).
• Reagent for the protection of amines and alcohols in multi-step organic synthesis.
• Building block for the production of agrochemicals such as herbicides and insecticides.
• Used in the preparation of polymerization initiators and specialty monomers.
• Intermediate in the synthesis of dyes and pigments.
• Reagent for peptide chemistry and other biochemical applications.
• Used in research and development for novel material science applications.

Basic Information

Product Name	1-Chloroethyl Chloroformate
CAS No.	50893-53-3
Molecular Formula	C3H4Cl2O2
Molecular Weight	142.97 g/mol
Synonyms	Chloroethyl chloroformate; 1-Chloroethyl carbonochloridate; Chloroformic acid 1-chloroethyl ester; Ethyl, 1-chloro-, chloroformate; Carbonochloridic acid, 1-chloroethyl ester; α-Chloroethyl chloroformate; (1-Chloroethoxy)carbonyl chloride
EINECS	256-847-5

Quality Control

Our 1-Chloroethyl Chloroformate is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C. Due to its highly volatile and reactive nature, keep away from heat, sparks, open flames, strong bases, and oxidizing agents. Use under an inert atmosphere and handle in a certified fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	1.30 - 1.35 g/mL
Refractive Index (n20D)	1.420 - 1.430

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.