Description

Pyrazinecarbonyl Chloride, 5-Methyl- (9Ci) is a versatile and reactive heterocyclic building block used in advanced organic synthesis. This compound is valued for its role as a key acylating agent, enabling the efficient introduction of the 5-methylpyrazinecarbonyl moiety into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyrazine core's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for organic electronic materials and metal-organic frameworks (MOFs).
• Peptide Mimetics and Conjugation: Facilitates the acylation of amines in peptides or other biomolecules to create conjugates for biochemical research.
• Custom Synthesis and Contract Manufacturing: A key reagent for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	Pyrazinecarbonyl Chloride, 5-Methyl- (9Ci)
CAS No.	50886-34-5
Molecular Formula	C6H5ClN2O
Molecular Weight	156.57 g/mol
Synonyms	5-Methylpyrazine-2-carbonyl chloride; 2-Pyrazinecarbonyl chloride, 5-methyl-; 5-Methyl-2-pyrazinecarbonyl chloride; 5-Methylpyrazinecarbonyl chloride; Methylpyrazinecarbonyl chloride; 5-Methylpyrazinoyl chloride
EINECS	Contact for details

Quality Control

Our Pyrazinecarbonyl Chloride, 5-Methyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and fine chemical research, and we can support custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.