Description

2-Chloro-4-Methyl-Nicotinoyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its dual functional groups, making it a versatile building block for constructing complex heterocyclic molecules. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nicotinic acid derivatives and other nitrogen-containing heterocycles with potential therapeutic activity.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, including herbicides and insecticides.
• Chemical Research & Development: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the production chain of specific APIs that require the 2-chloro-4-methyl-nicotinoyl moiety.
• Material Science: Potential use in the synthesis of specialized ligands for catalysis or functional materials.

Basic Information

Product Name	2-Chloro-4-Methyl-Nicotinoyl Chloride
CAS No.	50839-95-7
Molecular Formula	C7H5Cl2NO
Molecular Weight	190.03 g/mol
Synonyms	2-Chloro-4-methylnicotinoyl chloride; 2-Chloro-4-methylpyridine-3-carbonyl chloride; 3-Pyridinecarbonyl chloride, 2-chloro-4-methyl-; 2-Chloro-4-methylnicotinic acid chloride; 2-Chloro-4-methyl-3-pyridinecarbonyl chloride; Nicotinoyl chloride, 2-chloro-4-methyl-
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methyl-Nicotinoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.