Description

4-Quinolinecarbonyl Chloride is a versatile and highly reactive organic intermediate, specifically an acid chloride derivative of quinoline-4-carboxylic acid. Its primary value lies in its role as a key building block for synthesizing more complex quinoline-based compounds, enabling the introduction of the quinolinecarbonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to create active ingredients, advanced materials, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with quinoline scaffolds used in antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Employed in the production of advanced pesticides, herbicides, and fungicides, where the quinoline structure contributes to biological activity.
• Material Science Research: Used to create functionalized polymers, liquid crystals, and organic light-emitting diodes (OLEDs) by incorporating the quinoline unit.
• Dye and Pigment Manufacturing: Serves as a building block for synthesizing complex quinoline-based dyes and colorants.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Custom Synthesis and Contract Manufacturing: A valuable reagent for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Quinolinecarbonyl Chloride
CAS No.	50821-72-2
Molecular Formula	C10H6ClNO
Molecular Weight	191.61 g/mol
Synonyms	Quinoline-4-carbonyl chloride; 4-Carbamoylquinoline chloride; 4-Quinolinecarboxylic acid chloride; 4-Quinolylcarbonyl chloride; 4-Quinoline carbonyl chloride; Quinoline-4-carboxylic acid chloride; 4-Quinolinecarboxamide, N-chloro-; 4-Chlorocarbonylquinoline
EINECS	Contact for details

Quality Control

Our 4-Quinolinecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition from moisture. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.