Description

Polyphyllin D is a bioactive steroidal saponin primarily extracted from plants of the genus *Paris*, such as *Paris polyphylla*. This compound matters due to its significant pharmacological potential, particularly in exhibiting antitumor, anti-inflammatory, and antiviral activities. It is needed by researchers and manufacturers in the pharmaceutical, biotechnology, and nutraceutical industries for drug discovery, formulation development, and high-purity reference standard production.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the study and development of anticancer and anti-inflammatory therapeutics.
• Biomedical Studies: Used in in vitro and in vivo research to investigate mechanisms of apoptosis, cell cycle arrest, and modulation of signaling pathways like PI3K/Akt and MAPK.
• Natural Product & Herbal Medicine: A critical marker compound for the quality control and standardization of herbal extracts, particularly those derived from Paris polyphylla (Chonglou).
• Cosmeceutical Formulations: Explored for potential application in topical products targeting inflammation or skin conditions due to its anti-inflammatory properties.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting pharmacological screening and bioactivity assays.

Basic Information

Product Name	Polyphyllin D
CAS No.	50773-41-6
Molecular Formula	C51H82O21
Molecular Weight	1047.18 g/mol
Synonyms	Paris saponin VII; Polyphyllin VII; Chonglou saponin VII; Diosgenin 3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside; PPG D; PPD; (25R)-Spirost-5-en-3β-yl O-α-L-rhamnopyranosyl-(1→2)-O-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside
EINECS	Contact for details

Quality Control

Our Polyphyllin D is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and identity confirmation via spectroscopic methods (IR, MS, NMR), to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Solubility	Soluble in methanol, DMSO; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.