Description

1H-Indol-3-Yl)Acetyl Chloride is a highly reactive and versatile acid chloride derivative of indole, serving as a critical building block in advanced organic synthesis. Its primary value lies in enabling the efficient introduction of the indole-3-acetyl moiety, a key structural motif in bioactive molecules. This intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and life science industries who are developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of indole-based drug candidates, including potential neuroactive agents and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of novel plant growth regulators and pesticides that leverage the indole scaffold.
• Bioconjugation & Probe Development: Facilitates the labeling and modification of biomolecules for diagnostic and research applications due to its reactive acyl chloride group.
• Peptide & Heterocycle Chemistry: Employed in the construction of complex heterocyclic systems and the acylation of amino groups in peptide synthesis.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of specialized polymers with unique electronic or photophysical properties.

Basic Information

Product Name	1H-Indol-3-Yl)Acetyl Chloride
CAS No.	50720-05-3
Molecular Formula	C10H8ClNO
Molecular Weight	193.63 g/mol
Synonyms	3-Indoleacetyl chloride; (1H-Indol-3-yl)acetyl chloride; Indol-3-ylacetyl chloride; 2-(1H-Indol-3-yl)acetyl chloride; 3-Indolylacetic acid chloride; 1H-Indole-3-acetyl chloride; (Indol-3-yl)acetic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 1H-Indol-3-Yl)Acetyl Chloride is manufactured and tested under strict quality management protocols to ensure high purity and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.